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Björn Mattsson

I have a BSc and MSc in physics, built global machine learning products for a decade, and now provide consulting services in the field of computational chemistry. I am technology agnostic and believe that both modern ML methods and physics-based methods are valuable; the hard part is finding the right combination of tools for the problem at hand. I also believe that rigorous benchmarking is fundamental to make progress, both in individual projects and as a field.

Biography

Computational chemistry consultant

I started Enlace Bio in 2024 to provide computational chemistry services to biotechs and startups.

Public work:

  • Published a new benchmark for protein-ligand affinity prediction, co-authored with Pat Walters and covered by Derek Lowe in In The Pipeline. paper, code, dataset, In The Pipeline

  • OpenADMET blind PXR induction challenge: 4/100 in the structure prediction track (co-folding plus physics-based pose selection), 14/350 in the activity prediction track (ML, co-folding, semi-empirical QM). Invited as one of three teams to present the structure track approach in a webinar. structure track blogpost, activity track method report, webinar, final leaderboard

Professional experience in machine learning

I have spent a decade building ML products. At Tractable I as Head of Estimating AI helped build an AI-based computer vision product from early prototype to a globally deployed software platform, resulting in nine co-invented US patents. That experience gave me a practical understanding of what it takes to build ML systems for real-world usage.

 

Background in physics

My BSc thesis in computational quantum physics was published (>200 citations): paper.

Want to learn more?

​​Explore some of my code on Github.

Look at my Google Scholar profile.
Connect with me on LinkedIn.
Or get in touch below.

Would you like to get in touch?

  • Email
  • LinkedIn
  • GitHub

© 2026 Enlace Bio Ltd. Company no. 15870131, registered in England and Wales.

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